Inspired by nature and perfected by science, WinPep Sparin is the ultimate solution for soothing irritation and strengthening the skin's natural defense. Drawing on the resilience of microbes that thrive in extreme environments, WinPep Sparin is a groundbreaking peptide meticulously crafted using advanced Computer-Aided Drug Design (CADD) and Artificial Intelligence-based Drug Design (AIDD) technologies. Inspired by the unique properties of Sphingobacterium, this innovative peptide precisely targets the PAR-2 receptor, reducing neural sensitivity and enhancing the skin's tolerance threshold. In addition to its targeted soothing action, WinPep Sparin rapidly alleviates redness with potent anti-inflammatory effects while fortifying the skin barrier, ensuring a calm, revitalized complexion.
Function: Soothing, Anti-allergic, Anti-inflammation
Recommended use level: 1-20%
Product Literature
Inhibit the activation of PAR2-AKT-NF-κB-proinflammatory cytokines pathway.
Effectively decrease the level of PAR-2 after UV radiation.
Significantly decrease the level of Ca2+ by 34.6% after UV radiation.
Significantly decreasethe level of AKT by 36.6% after UV radiation.
Significantly decreasethe level of NF-κB by 36.1% after UV radiation.
Significantly decrease the content of TNF-α and IL-6 by 97.1%, 55.6%, respectively, after LPS stimulation.
Rapidly improve redness within 60 minutes, alleviating skin irritation.
Repair skin barrier, reducing △TEWL for 120 minutes.