WKPep®Multi-soothing peptides


WKPep® Multi-Soothing Peptides is a powerful soothing peptide complex designed to combat itching, discomfort, and irritation while promoting skin health and reducing sensitivity. It offers a comprehensive solution for sensitive and reactive skin. Its soothing and anti-sensitivity effects are attributed to dual mechanisms: anti-inflammation and nerve regulation. WKPep® Multi-Soothing Peptides binds to MC1-R, exerting a potent anti-inflammatory effect—shown in vitro to be 30 times stronger than that of dexamethasone. Additionally, it reduces nerve sensitivity by inhibiting the activation of TRPV-1, a key receptor involved in transmitting sensations of itching, pain, and burning. By blocking stimuli such as heat and acid, it helps raise the skin’s tolerance threshold and calms hypersensitive reactions.


INCI Name: Palmitoyl Tripeptide-8, Acetyl Tetrapeptide-15

Function: Anti-allergic, Anti-inflammation, Skin soothing

Recommended use level: 0.2~5%


Product Literature

Evaluation of efficacy


In vitro test


Significantly anti-inflammation by decreasing the release of inflammatory factor IL-6, IL-8, TNF-α, better effect than dexamethasone.


In vivo test


Relieves histamine-irritant symptoms after 0.5 hour and 1.5 hours, completely recovers after 2 hours.

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