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WKPep®Salaregen S


Developed with cutting-edge drug development technology, WKPep® Salaregen S is a groundbreaking bioactive peptide with a novel molecular structure. Inspired by the regenerative peptide found in the skin of amphibians— remarkable creatures with extraordinary renewal potential—it offers exceptional skin-repair and rejuvenation benefits. WKPep® Salaregen S promotes collagen-rich, youthful, smooth, and firm skin while visibly reducing the signs of aging. As a safe EGF substitute, it activates cell viability and stimulates cell proliferation from the epidermis to the dermis, replenishing collagen to restore skin vitality. Additionally, it soothes and calms the skin by inhibiting the release of inflammatory factors, improving redness, and enhancing overall skin comfort. Its protective properties further strengthen the skin barrier, repair photodamaged cells, resist UV damage, and combat irritation, ensuring a healthier and more resilient complexion.


INCI Name: Oligopeptide-215

Function: Anti-wrinkle, Anti-aging, Skin repairing

Recommended use level: 1-10%


Product Literature

Evaluation of efficacy


In vitro test


Increase HaCaT & NIH3T3 cellular viability.

Promote migration of HaCaT, as effective as EGF.

Anti-inflammation, inhibit proinflammatory cytokines IL-6, IL-8, TNF-α production and the expression of NF-κB.

Repair photoaging cell, protect skin from external damage.

Boost Collagen I synthesis.


In vivo test


Reduce transepidermal water loss (TEWL), repair and strengthen skin barrier, better effect than EGF.

Improve erythema for 3 days after stimulation with 3% SDS.

Enhance skin elasticity in 28 days and has the similar effect to EGF.

Reduce nasolabial folds length & area, and the depth, length and area of crow's feet in 28 days.


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