WKPep®Caffytide S


WKPep®Caffytide S is a patented innovative peptide that combines an ECM-boosting Hexapeptide with the natural antioxidant caffeic acid. Developed using advanced CADD and Peptide Drug Conjugate (PDC) technologies, it offers exceptional skin rejuvenation benefits, reducing the appearance of wrinkles and enhancing overall skin tone and smoothness. This unique peptide works by targeting MMP2, the enzyme responsible for collagen breakdown, helping to preserve and stimulate the production of essential skin proteins—collagen types I, III, IV, and laminin. Coupled with its potent antioxidant properties, WKPep®Caffytide S shields the skin from oxidative stress caused by UV radiation and pollution, fortifying skin structure and defending against environmental damage.


INCI Name: Caffeoyl hexapeptide 9

Function: Anti-wrinkle, Anti-aging, Skin repairing

Recommended use level: 1-5%


Product Literature

Evaluation of efficacy


In vitro test


Inhibits the production of MMP2 following UV radiation.

Significantly increases the synthesis of collagen types I, III, and IV by 18.6%, 22.8% and 62.9% after UV radiation.

Antioxidant Activity: Exhibits significant DPPH clearance.

Enhances cell viability after exposure to UV radiation.

Elevates the levels of LAMa2 by 40.2%, a protein important for skin structure, after UV radiation.



In vivo test


Reduces the appearance of wrinkles within 14 days.

Diminishes dark circles in 28 days.

Enhances skin elasticity and firmnees in only 14 days.



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